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McCarthy is back in a boot and probably will not be able to play....that's a big blow. However, it looks like Zac Diles will step up in his place. He's been playing much better than many of us thought at the beginning of the season.
Defensive Line -
Jurrell Casey is expected to play but has been banged up all season....good thing Mike Martin has stepped up to the plate in a HUGE way. If he and Casey can stay healthy the will be a force for years to come.
The Bills have an offensive line that isn't at full health so (hopefully) guys like Derrick Morgan and Kamerion Wimbley along with Casey, Marks, and Martin can put some pressure on Ryan Fitzpatrick and limit CJ Spiller.
Stop the Tight End -
We have yet another game where the tight end has been on fire even when they aren't playing Tennessee.
Enter Scott Chandler.
Chandler has 219 yards and 4 touchdowns on the season. Somebody has got to get a hat on this guy and make sure he doesn't have a career day against us. If you give him a free release or take your eyes off of him he's going to have a big day.