| Tennessee Titans (2-2) | Game #5 | New York Giants (1-2) |
| Date: | October 10, 2010 | Location: | Arlington, TX |
| Time: | 3:15 PM | Stadium: | Cowboys Stadium |
| TV: | CBS | Weather: | 80 degrees,10% rain chance, 10 mph SSW |
| Radio: | 104.5 WGFX | Line: | Cowboys -6.5 |
| SB Nation: | Blogging The Boys | MSM Coverage: | Star Telegram |