The Titans do not have a history of being a fantasy juggernaut, but this year they have quite a few guys that could be relevant to your fantasy match-ups this week. You have to start Chris Johnson in this one. Now I would argue that you should be starting CJ every week because you had to spend a first or second round pick to get him. You aren't taking guys that high to only play them when they have a good match-up.
With that being said, CJ should be in line for a big game here. The Texans are going to play a lot of man coverage. That means Johnson will have some opportunities in space if he can beat a stacked box.
Speaking of Houston playing man coverage, Kenny Britt should be able to dominate anyone the Texans can put on him. It will just be up to Jake Locker to give him some opportunities.
Kendall Wright could be a sneaky good play in a deep league. He will also really benefit from one on one coverage.
I would sit the Titans defense this week (not sure why you would even own them). Sure, they looked great in Pittsburgh, but that offense is terrible. Things will not be as easy against the Texans.